In the biopharmaceutical industry, centrifugal extractor is commonly used equipment for extraction unit operations, especially for the extraction of pharmaceutical intermediates and APIs. Moreover, the process of centrifugal extractor is very mature in this field, and the extraction effect is also very good.
Centrifugal extractor is mainly used in extraction, stripping, acid washing, alkali washing, water washing and other processes in biopharmaceutical extraction. The production of a drug requires a complete set of process flows, and the basic process is probably chemical raw materials--intermediates--APIs--prepared finished drugs. This also requires synthesis, cooling, filtration, centrifugal separation, distillation, drying and other processes. Centrifugal extractor is used in the extraction and separation process to extract the required pharmaceutical intermediates.
Process flow of centrifugal extractor in biopharmaceutical extraction process
The feed liquid is injected into the centrifugal extractor through different inlets. In the mixing area, the feed liquid is quickly mixed and dispersed through the turbine disc and impeller with the help of the rotation of the drum, and the two-phase liquid is fully transferred to complete the mixing and mass transfer process. The mixed feed liquid enters the drum under the action of the vortex disc. Under the action of centrifugal force, the two phases are separated. The clarified two-phase liquid finally enters the collection chamber through their respective weir plates and is led out of the machine by the guide pipes to complete the two-phase separation process.
The CWL-M centrifugal extractor independently developed by Zhengzhou Tiei Extraction is a new, efficient and energy-saving liquid-liquid extraction separation equipment. When the extraction process is used in the biopharmaceutical industry, especially when many stages are required or non-equilibrium extraction can be used, the application effect of the centrifugal extractor is better.
The use of centrifugal extractor has significant effects on reducing the footprint of extraction equipment, reducing the amount of extractant retained in the extraction process, shortening the time from start-up to stabilization of the extraction system, and facilitating automatic control. It is also widely used in other traditional industries to replace traditional extraction equipment, and has a very good application prospect.
CWL-M centrifugal extractors are generally divided into laboratory equipment and industrial equipment. Laboratory centrifugal extractor is mainly used for small-scale experiments before industrial procurement. When the experimental data meets the customer's production requirements, the process is enlarged and industrial equipment is purchased.
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